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US 2022/0064670 A1Published application
Oncolytic virus expressing interferon and application therefor
AssigneeShanghai Yuansong Biotechnology Co. Ltd.
InventorsKangjian ZHANG, Xianlong FANG, Jinfa GU, Xinyuan LIU
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Abstract
Provided is an oncolytic virus expressing interferon. Specifically provided is an oncolytic adenovirus comprising a fusion protein expressing interferon, said oncolytic virus being capable of effectively suppressing tumors in vitro and in vivo.
Claims20
An oncolytic virus comprising a nucleic acid encoding interferon, wherein the interferon is selected from the group consisting of interferon-α, interferon-β, interferon-γ or consensus interferon, and wherein the virus is an adenovirus.
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Dependencies are inferred from the claim text.