US 2022/0064635 A1 · CRISPR COMPOSITIONS AND METHODS FOR PROMOTING GENE EDITING OF ADENOSINE DEAMINASE 2 (ADA2)

Abstract

RNA molecules comprising a guide sequence portion having 17-25 nucleotides in the sequence of 20-22 contiguous nucleotides set forth in any one of SEQ ID NOs: 1-12655 and compositions, methods, and uses thereof.

Claims37

Dependent claims

An RNA molecule comprising a guide sequence portion having 17-25 nucleotides comprising the sequence of 20-22 contiguous nucleotides set forth in any one of SEQ ID NOs:

1-12655.

Dependencies are inferred from the claim text.

Facts

Application

17/420,934Filed 6 Jan 2020

Priority

7 Jan 2019

Published

3 Mar 2022

Term ends

Not estimatedThe source records don’t support an estimate.

Classification11 codes

C12N 15/11
Recombinant DNA-technology: dNA or RNA fragments; Modified forms thereof ; Non-coding nucleic acids having a biological activity
C12N 15/90
Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation: stable introduction of foreign DNA…
A61K 35/28
Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically…:…
C12N 9/226
Clustered regularly interspaced short palindromic repeats [CRISPR]-associated [CAS] enzymes: class 2 CAS enzyme complex, e.g. single CAS protein

Crispr compositions and methods for promoting gene editing of adenosine deaminase 2 (ada2)

Life of this patent

Abstract

Claims37

Crispr compositions and methods for promoting gene editing of adenosine deaminase 2 (ada2)

Life of this patent

Abstract

Claims37