US 2022/0064612 A1 · PaCas9 nuclease

PaCas9 nuclease

AssigneeJoint Stock Company “Biocad”

InventorsDmitriy Aleksandrovich MADERA, Aleksandr Vladimirovich KARABELSKII, Roman Alekseevich IVANOV, Dmitry Valentinovich MOROZOV, Konstantin Viktorovich SEVERINOV, Sergey Anatolevich SHMAKOV, Dmitrii Aleksandrovich SUTORMIN, Georgii Evgenevich POBEGALOV, Aleksandra Andreevna VASILEVA, Polina Anatolevna SELKOVA, Anatolii Nikolaevich ARSENIEV, Tatyana Igorevna ZYUBKO, Iana Vitalevna FEDOROVA

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Abstract

The present invention relates to the field of biotechnology, molecular biology and medicine, in particular to nuclease enzyme and use thereof. More specifically, the present invention relates to PaCas9 nuclease enzyme. The invention also relates to a nucleic acid encoding said nuclease, a genetic construct, an expression vector, a delivery vector, which comprise said nucleic acid, a liposome comprising said nuclease or nucleic acid encoding said nuclease, a method for producing a nuclease, methods for delivery, and a host cell comprising a nucleic acid encoding said nuclease.

Claims10

Dependent claims

PaCas9 nuclease having an amino acid sequence of SEQ ID NO:

Dependencies are inferred from the claim text.