US 2022/0064186 A1Published application

Crystalline forms of a par4 inhibitor

AssigneeBristol-Myers Squibb Company

InventorsRoxana F. Schlam, Nicolas Cuniere, Victoria A. Mbachu, Zhongping Shi, Petinka I. Vlahova

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Abstract

The present invention relates to co-crystals of the compound of formula (I), wherein the co-former molecule is succinic acid or citric acid, processes for the preparation of the co-crystal, pharmaceutical compositions thereof, and methods of using the co-crystals for treating or preventing thromboembolic disorders.

Claims16

Dependent claims

A co-crystal of the compound of Formula (1)

and a co-former, wherein the co-former is succinic acid or citric acid.

Dependencies are inferred from the claim text.

Facts

Application: 17/415,237Filed 20 Dec 2019
Priority: 21 Dec 2018
Published: 3 Mar 2022
Term ends: Not estimatedThe source records don’t support an estimate.

Classification12 codes

C07D 513/04
In which the condensed system contains two hetero rings: ortho-condensed systems
A61K 31/433
Having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole: thidiazoles
A61K 45/06
Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00: mixtures of active ingredients without…
A61P 7/02
Drugs for disorders of the blood or the extracellular fluid: antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Family

Application62/783,223Us provisional application · filed 21 Dec 2018
US 12,129,264 B2Related patent
US 2022/0064186 A1This patent

From the US filing history. Foreign family members aren’t listed.

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