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US 2022/0055033 A1Published application
Self-Contained Nucleic Acid Processing
AssigneesBioFire Diagnostics, LLC, BioFire Defense, LLC
InventorsKyle K. Johnson, Owen D. Brimhall, Jonathan J. Politis
Life of this patent
Estimating the term…
Abstract
Instruments and methods for amplifying nucleic acids in a sample provided in a flexible, self-contained, substantially closed sample container.
Claims12
An instrument for processing a sample, comprising
- a first support member and a second support member;
- an opening for receiving a flexible reaction container between the first support member and the second support member, the container comprising:
- a loading attachment,
- a plurality of reaction zones, and
- one or more sealable flow paths, each having a first side connecting the loading attachment to one or more fill ports, at least one of which is configured for receiving the sample, and a second side connected to at least one of the plurality of reaction zones, the sealable flow paths providing the only access from the one or more fill ports to the plurality of reagent zones such that when the first side of all of the one or more sealable paths are sealed, the container is fully closed;
- a plurality of heat seal elements provided on at least one of the support members so as to contact the loading attachment and the one or more sealable flow paths, wherein the heat seal elements include a number of individually controlled heater elements associated with each of the first side of the one or more sealable flow paths.
3 more elements
Dependencies are inferred from the claim text.