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OwnerAmir Lichtenstein, Noel Axelrod +2inventors
InventorsAmir Lichtenstein, Noel Axelrod, Ove Vincent Solesvik, Chai Ezerzer
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The present disclosure relates to a cell extraction device comprising: a plurality of cell extraction modules arranged in a single layer array, the single layer array having a cell-receiving side wherein an opening of at least one of the plurality of cell extraction modules on the cell-receiving surface is configured to receive and retain a single target cell from a fluid sample, and a fluid-evacuating side wherein an opening of the or each of the plurality of cell extraction modules on the fluid-evacuating side is configured to allow fluid from the fluid sample to be evacuated from the cell extraction device, wherein at least one of the plurality of cell extraction modules comprises a micropore capillary configured at a first end that is open on the cell-receiving side to receive a target cell, and configured at a second end that is open on the fluid-evacuating side to allow fluid to pass through.
A cell extraction device comprising:
The cell extraction device of any preceding claim, wherein each of the plurality of cell extraction modules comprises a micropore capillary.
The cell extraction device of any preceding claim, wherein at least one micropore capillary is configured with the first end wider than the second end, wherein the dimension of the first end of the capillary corresponds to or is smaller than the dimension of a single target cell, and the second end is so dimensioned to be smaller than the dimension of a single target cell to prevent a target cell received by the first end to pass through.
The cell extraction device of any preceding claim, wherein the first ends of a first portion of the plurality of micropore capillaries are of a first dimension that corresponds to or is smaller than the dimension of a first target cell, and the first ends of a second portion of the plurality of micropore capillaries are of a second different dimension that corresponds to or is smaller than the dimension of a second different target cell.
The cell extraction device of any preceding claim, wherein the first end of at least one micropore capillary is formed into a well in fluid communication with the micropore capillary, wherein the opening of the or each well is wider than the first end of the micropore capillary.
The cell extraction device of any preceding claim, wherein at least one of the plurality of cell extraction modules is labelled with a unique identification tag.
The cell extraction device of any preceding claim, wherein the device is formed in the shape of a disc with a material selected from a group comprising silicon, AlGaN/GaN, a photoresist, other semiconductor material, or a combination thereof, or novel compound materials suitable for forming three dimensional patterns using micro-printing, injection moulding, stamping, and/or flexographic printing.
A cell analysis system comprising:
Dependencies are inferred from the claim text.