Systems and Methods for Performing Biological Assays

A system for performing a biological assay, the system comprising:

• a. a sample preparation device comprising:
• i. a sample receiving module comprising a fluid container comprising a preparation solution;
• ii. a cap removably coupleable to the sample receiving module;
• and
• iii. a valve or a breakable seal operatively coupled to the sample receiving module;
• b. an optical property modifying device operatively coupleable to the sample preparation device and comprising:
• i. a sample receiving cartridge operatively coupled to the valve or the breakable seal comprising one or more reaction chambers each comprising an optical property modifying reagent;
• ii. a substrate comprising a heating element:
• wherein when the optical property modifying device is operatively coupled to the sample preparation device and the valve is actuated from a sealed to unsealed conformation or the breakable seal is broken, the sample receiving module transmits at least a portion of the preparation solution through the valve or the breakable seal into the one or more reaction chambers.

A system for performing a biological assay, the system comprising:

• a. a sample preparation device comprising:
• i. a sample receiving module comprising a fluid container comprising a preparation solution;
• ii. a pressurizing chamber comprising a plunger, wherein the pressurizing chamber is operatively coupled to the sample receiving module;
• b. an optical property modifying device operatively coupleable to the sample preparation device and comprising:
• i. a sample receiving cartridge operatively coupled to the sample preparation device, comprising one or more reaction chambers each comprising an optical property modifying reagent;
• ii. a substrate comprising a heating element:
• wherein when the optical property modifying device is operatively coupled to the sample preparation device and the plunger is actuated the plunger creates positive pressure in the pressurizing chamber or sample receiving module to transmit at least a portion of the preparation solution from the sample receiving module into the one or more reaction chambers of the sample receiving cartridge, thereby depressurizing the sample receiving module.