Noninvasive electrical treatment devices

A noninvasive electrical treatment device comprising:

• a first bipole electrode pair aligned along a first axis;
• a second bipole electrode pair aligned along a second axis, the first axis and the second axis defining a plane;
• a focused ultrasound (FUS) transducer configured to direct a focused ultrasound beam along a third axis that intersects the plane;
• a controller electrically coupled to the first and second bipole electrode pairs and to the focused ultrasound transducer, the controller configured to:
• apply electrical energy having a frequency of between about 1 Hz to about 100 MHz to the first and second bipole electrode pairs;
• and
• cause the FUS transducer to emit a focused ultrasound beam having a frequency of between about 20 kHz to about 10 MHz.

A device comprising:

• an array of electrodes disposed around a central region, the electrodes configured to apply electrical current transcutaneously to a treatment site;
• a focused ultrasound (FUS) transducer disposed in the central region, the FUS transducer configured to apply focused ultrasonic energy to the treatment site;
• and
• a controller electrically coupled to the array of electrodes and to the FUS transducer, the controller configured to apply electrical energy to the array of electrodes and to cause the FUS transducer to emit a focused ultrasound beam.