Back to results
US 2022/0054710 A1Published application
Decellularization of Plant Cell Culture Materials for Tissue Engineering and Drug Delivery
AssigneeWorcester Polytechnic Institute
InventorsJeannine Coburn, Glenn Gaudette, Nhi Phan
Life of this patent
Estimating the term…
Abstract
Provided herein are enzymatically decellularized cells, and methods of producing said cells, that can be used in a scaffold. The scaffolds featured herein are biocompatible and can comprise decellularized cells that have been modified to express a bioactive agent or molecule.
Claims18
A method for decellularizing cells, the method comprising:
- contacting a plurality of cells with a composition comprising a nuclease, thereby decellularizing the plurality of cells, wherein the plurality of cells are cellulose producing cells.
A scaffold comprising decellularized cells derived from a cellulose producing organism and a bioactive molecule.
-13. (canceled)
A method of producing a biocompatible scaffold, the method comprising:
- contacting the cellulose producing cells with a composition comprising a nuclease, thereby producing decellularized cells;
- and
- creating a scaffold from the decellularized modified cells.
Dependencies are inferred from the claim text.