Nanoparticles and compositions for biological imaging based on x-ray attenuation
AssigneeKookmin University Industry Academy Cooperation Foundation
InventorsSanggyu YIM, Ilhwan RYU, Jee-Yeon RYU
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Abstract
The present invention relates to an X-ray attenuation-based biometric imaging technology and includes a core structure comprising an X-ray attenuating material; and a shell layer formed on the core structure and made of a material having biocompatibility and non-reactivity in vivo, and it has the effect of enabling simple and rapid cancer diagnosis by plain X-ray imaging, such as those used for non-invasive chest X-ray.
Claims14
Nanoparticles for biological imaging based on X-ray attenuation comprising:
- a core structure comprising an X-ray attenuating material;
- and
- a shell layer formed on the core structure and made of a material having biocompatibility and non-reactivity in vivo.
A method of preparing nanoparticles for biological imaging based on X-ray attenuation comprising:
- preparing an X-ray attenuating material precursor solution (Step 1);
- preparing a core structure by adding the solution of the step 1 to a core precursor solution (Step 2);
- annealing the core structure of the step 2 (Step 3);
- and
- preparing nanoparticles having a core precursor-shell layer by adding annealed core structure of the step 3 to a shell precursor solution (Step 4).
Dependencies are inferred from the claim text.