Choline acetyltransferase as a therapy for hypertension
AssigneeThe Feinstein Institutes for Medical Research
InventorsKevin J. Tracey, Sangeeta S. Chavan, Andrew Stiegler, Jian Hua Li
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Abstract
Compositions and methods are provided comprising choline acetyltransferase (ChAT) and PEGylated ChAT for treating hypertension.
Claims27
A method of reducing systemic hypertension in a subject in need thereof comprising administering to the subject a choline acetyltransferase (ChAT) or a ChAT conjugated to polyethylene glycol (PEG) in an amount and manner effective to reduce systemic hypertension in a subject.
A pharmacological composition comprising choline acetyltransferase (ChAT) conjugated to polyethylene glycol (PEG) and a pharmaceutically acceptable carrier.
Dependencies are inferred from the claim text.