Methods of treating of inflammatory bowel disease and parasite infection
AssigneePresident and Fellows of Harvard College
InventorsWendy Garrett, Michael Howitt
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Abstract
Described herein are methods for the induction of a TH2 immune response and for the treatment and/or prevention of diseases associated with pathological immune responses and parasitic infection.
Claims18
A method of inducing a type 2 helper T cell (TH2) immune response in a subject comprising administering to the subject a small molecule that enhances the activity or expression of Trpm5.
A method of treating or preventing an inflammatory bowel disease in a subject comprising administering to the subject a small molecule that enhances the activity or expression of Trpm5.
A method of treating or preventing a parasitic infection in a subject comprising administering to the subject a small molecule that enhances the activity or expression of Trpm5.
Dependencies are inferred from the claim text.