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US 2022/0054586 A1Published application
Liquid composition comprising protein
AssigneeSamsung Bioepis Co., Ltd.
InventorsInae KIM, Soyun JUNG, Jaemin LEE, Hun Joo LEE, Yongkook KIM
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Abstract
The present invention relates to a protein-stabilized liquid formulation and provides: a composition for protein stabilization, the composition including a stabilizer and a surfactant and not including a buffer; a protein liquid composition including the composition for stabilization and a protein; and a method of producing a protein-stabilized liquid composition which uses the composition for stabilization.
Claims27
A liquid composition comprising:
- (1) 5 mg/ml to 300 mg/ml of a protein;
- (2) a stabilizer comprising at least one selected from the group consisting of a polyol and a sugar;
- and
- (3) a surfactant,
- wherein, a pH of the liquid composition is in a range of 4 to 8.
2 more elements
-21. (canceled)
(canceled)
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A liquid composition comprising:
- (1) aflibercept;
- (2) a stabilizer comprising at least one selected from the group consisting of a polyol and a sugar;
- and
- (3) a surfactant,
- wherein a pH of the liquid composition is in a range of 5.7 to 6.7.
2 more elements
(canceled)
(canceled)
(canceled)
Dependencies are inferred from the claim text.