Formulation comprising water soluble particles of a non-curcuminoid and a curcuminoid
AssigneesStabicon Life Sciences Pvt. Ltd., Lyrus Life Sciences Pvt. Ltd., Nokha Trading LLP
InventorsVijay Kumar RANKA, Malini SHARMA, Pranab Kumar PATRA, Gulabusein SOUDAGAR, Yashvanth G, Hemanth Kumar BOTHRA, Shrinivasan Shesha IYENGAR
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Abstract
Embodiments relate to a formulation comprising a particle comprising a turmeric oleoresin or a curcumin removed turmeric oleoresin or a turmeric oil or combination thereof wherein the composition is water-soluble and therapeutically safe, wherein the composition does not contain a pH buffer, and wherein the composition further comprises a curcuminoid.
Claims20
A formulation comprising a composition comprising a particle comprising a turmeric oleoresin or a curcumin removed turmeric oleoresin or a turmeric oil wherein the composition is water soluble and therapeutically safe, wherein the composition does not contain a pH buffer, and wherein the composition further comprises a curcuminoid.
A formulation comprising a particle comprising a curcuminoid, a non-curcuminoid and a lipophilic solvent.
A water-soluble formulation comprising a curcuminoid and a non-curcuminoid, or pharmaceutically acceptable salts or derivatives thereof, wherein the water-soluble formulation is both therapeutically safe and stable in a form of the water-soluble formulation.
A water-soluble formulation comprising a first particle comprising a curcuminoid and a second particle comprising curcumin-removed turmeric oleoresin or turmeric oil comprising a non-curcuminoid, or pharmaceutically acceptable salts or derivatives thereof, wherein the water-soluble formulation is both therapeutically safe and stable in a form of the water-soluble formulation.
A formulation comprising a composition comprising a curcuminoid and a non-curcuminoid, wherein the composition has properties as follows:
- a) solubilization of the curcuminoid in a turmeric oleoresin or a curcumin removed turmeric oleoresin or a turmeric oil or combination thereof resulting in a clear solution having a percent sediment load of less than 30%;
- b) solubilization in the turmeric oleoresin or the curcumin removed turmeric oleoresin or the turmeric oil or combination of the curcuminoid and the non-curcuminoid having particles having an average number particle size in a range of 40 to 1000 nm;
- c) the formulation exhibits no precipitation or separation of the particles for a minimum period of 24 hours;
- d) the formulation exhibits no precipitation or separation of the particles for a minimum period of 15 minutes when added to water in a ratio of one part of the formulation in 200 parts of water.
A method comprising:
- a) mixing a curcuminoid, a curcumin removed turmeric oleoresin and a non-ionic emulsifier to form a blend;
- b) sonicating and resting the blend alternatingly to obtain a clear solution;
- c) preparing a water-soluble curcuma formulation.
Dependencies are inferred from the claim text.