Methods and compositions for treatment of lysosomal storage disorders
AssigneeJme Group Associates Inc.
InventorsFrank Martiniuk, Elena Arvanitopoulos, John Arvanitopoulos, Angelo Kambitsis
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Abstract
This application relates to the treatment of lysosomal storage disorders resulting from a deficiency of acid maltase and/or acid α-glucosidase by administering active barley in comminuted form. Also disclosed are methods of replacing acid maltase and/or acid α-glucosidase by administering active barley in comminuted form. Further disclosed are compositions for carrying out these methods.
Claims24
A method of treating a lysosomal storage disease resulting from a deficiency of acid maltase and/or acid α-glucosidase, said method comprising:
- selecting a subject having a lysosomal storage disease resulting from a deficiency of acid maltase and/or acid α-glucosidase and
- administering active barley in comminuted form to the selected subject to treat the lysosomal storage disease.
A method of replacing acid maltase and/or acid α-glucosidase in a subject, said method comprising:
- selecting a subject in need of replacing acid maltase and/or acid α-glucosidase and
- administering active barley in comminuted form to the selected subject to replace acid maltase and/or acid α-glucosidase in the selected subject.
A therapeutic composition comprising:
- active germinated barley in comminuted form and
- an edible pharmaceutically acceptable carrier.
A therapeutic system comprising:
- active germinated barley in comminuted form and
- an enzyme replacement therapeutic.
Dependencies are inferred from the claim text.