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US 2022/0054550 A1Published application
Combination therapies
AssigneeMemorial Sloan Kettering Cancer Center
InventorsEric L. Smith, Renier J. Brentjens
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Abstract
The presently disclosed subject matter provides combination therapies for treating diseases or disorders, e.g., cancers. In particular, the present disclosure provides methods of treatment comprising administering genetically engineered cells and radiation.
Claims34
A method of treatment, comprising:
- (a) administering to a subject having a disease or condition a dose of cells expressing a recombinant receptor that binds to an antigen;
- and
- (b) administering to said subject radiation, wherein initiation of administration of the radiation is no later than about two weeks after administration of the recombinant receptor-expressing cells.
Dependencies are inferred from the claim text.