Nitric oxide topical application apparatus and methods
AssigneeSyk Technologies, LLC
InventorsC. Michael Miller, Gordon K. Hill, A. John Pate, David A. Bell
Life of this patent
Estimating the term…
Abstract
A topical application of nitric oxide may be provided by two separate containers, each containing an active component media to produce nitric oxide when combined. For example, a nitrite component media may be contained in one dispenser and an acidified component media may be contained in another dispenser. Each dispenser may dispense the respective component media as a foam or a solution. They can be combined to initiate the production of nitric oxide and the mixture of resultant foam is applied topically to treat various skin disorders or wounds.
Claims20
A method for transdermal delivery of nitric oxide comprising:
- providing a first solution comprising water, a nitrite reactant, and a cationic surfactant;
- providing a second solution comprising water, an acid reactant, and the cationic surfactant;
- dispensing a portion of the first solution in a manner that produces a first foam;
- dispensing a portion of the second solution in a manner that produces a second foam;
- mixing the first foam and the second foam to produce a resultant foam, wherein the resultant foam comprises bubbles containing nitric oxide;
- applying the resultant foam to a portion of skin, wherein the portion of skin has at least one of a temperature, a texture, and an acid mantle;
- and
- bursting a portion of the bubbles on the portion of skin by at least one of the portion of skin's temperature, texture and acid mantle.
A method for treating skin disorders comprising:
- providing a first solution comprising approximately 100 mL of water, 10 g of sodium nitrite, and 2 g of a cationic surfactant;
- providing a second solution comprising approximately 100 mL of water, 5 g of lactic acid, 6 g of citric acid, and 6 g of the cationic surfactant;
- dispensing a portion of the first solution in a manner that produces a first foam;
- dispensing a portion of the second solution in a manner that produces a second foam;
- mixing the first foam and the second foam to produce a resultant foam, wherein the resultant foam comprises bubbles containing nitric oxide;
- applying the resultant foam to a portion of skin, wherein the portion of skin has at least one of a temperature, a texture, and an acid mantle;
- and
- collapsing the resultant foam on the portion of skin.
A method for transdermal delivery of nitric oxide comprising:
- providing a first solution comprising water, a nitrite reactant, and a cationic surfactant;
- providing a second solution comprising water, an acid reactant, and the cationic surfactant;
- dispensing a portion of the first solution;
- dispensing a portion of the second solution;
- mixing the first solution and the second solution to produce a resultant foam, wherein the resultant foam comprises bubbles containing nitric oxide;
- applying the resultant foam to a portion of skin, wherein the portion of skin has at least one of a temperature, a texture, and an acid mantle;
- bursting a portion of the bubbles on the portion of skin by at least one of the portion of skin's temperature, texture and acid mantle;
- and
- collapsing the resultant foam on the portion of skin.
Dependencies are inferred from the claim text.