Animal treatments
AssigneeNewMarket Pharmaceuticals LLC
InventorsDavid Rock, Mark Ridall
Life of this patent
Estimating the term…
Abstract
Compositions and methods for the treatment and control of various conditions in an animal which comprises administering to said animal an effective amount of an immediate release composition of about 0.5% to 50% wt/wt of active ingredient together with excipients to a total of about 100%, wherein said composition dissolves in a relatively short period of time, e.g., 75 seconds or less, 5 seconds or less, or 3 seconds or less, upon administration to said animal.
Claims20
A method of treating pulmonary edema, congestive heart failure, or exercise-induced pulmonary hemorrhage in an animal in need thereof, the method comprising:
- determining a dose of furosemide required;
- and
- administering orally to a pre-gastric mucosal cell of the animal a Direct Systemic Introduction (DSI) composition comprising the furosemide;
- wherein the DSI composition in the animal's oral cavity is dissolved in less than about 75 seconds;
- and
- wherein the required dose of the furosemide is determined by greater than 50% of the administered furosemide being detected in the animal's circulatory system via the pre-gastric mucosal cells lining the animal's alimentary canal prior to the animal's secretory stomach.
A method of promoting diuresis or treating an allergic reaction in an animal in need thereof, the method comprising:
- determining a dose of furosemide required;
- and
- administering orally to a pre-gastric mucosal cell of the animal a Direct Systemic Introduction (DSI) composition comprising the furosemide,
- wherein the DSI composition in the animal's oral cavity is dissolved in less than about 75 seconds, and
- wherein the required dose of furosemide is determined by greater than 50% of the administered furosemide being detected in the animal's circulatory system via the pre-gastric mucosal cells lining the animal's alimentary canal prior to the animal's secretory stomach.
Dependencies are inferred from the claim text.