Compounds and methods for treating viral infections
AssigneeLexicon Pharmaceuticals, Inc.
InventorsSuma GOPINATHAN, Praveen TYLE, Qi Melissa YANG
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Abstract
Provided herein are methods of treating, managing and/or preventing viral infections. A particular method comprises administering to a subject in need thereof an effective amount of an adaptor associated kinase 1 inhibitor of Formula (I):
Claims5
1-21. (canceled)
A method of treating, managing or preventing a SARS-CoV-2-like coronavirus infection, the method comprising administering to a subject in need thereof a therapeutically or prophylactically effective amount of a compound, wherein the compound is (S)-1-((2′,6-bis(difluoromethyl)-[2,4′-bipyridin]-5-yl)oxy)-2,4-dimethylpentan-2-amine:
- or a pharmaceutically acceptable salt thereof.
A method of treating, managing or preventing a CoV-229E-like coronavirus infection, the method comprising administering to a subject in need thereof a therapeutically or prophylactically effective amount of a compound, wherein the compound is (S)-1-((2′,6-bis(difluoromethyl)-[2,4′-bipyridin]-5-yl)oxy)-2,4-dimethylpentan-2-amine:
- or a pharmaceutically acceptable salt thereof.
A method of treating, managing or preventing a CoV-OC43-like coronavirus infection, the method comprising administering to a subject in need thereof a therapeutically or prophylactically effective amount of a compound, wherein the compound is (S)-1-((2′,6-bis(difluoromethyl)-[2,4′-bipyridin]-5-yl)oxy)-2,4-dimethylpentan-2-amine:
- or a pharmaceutically acceptable salt thereof.
25-27. (canceled)
Dependencies are inferred from the claim text.