Personalized methods of treating cancer
AssigneeFaeth Therapeutics, Inc.
InventorOliver D.K. Maddocks
Life of this patent
Estimating the term…
Abstract
Disclosed herein are dietary compositions that are substantially devoid of at least cysteine or a salt thereof for use in treating a cancer. The dietary compositions and methods of the disclosure can be used to treat cancers that are MTAP-deficient, alone or in combination with a cancer therapy.
Claims21
A method for treating a cancer in a subject in need thereof, the method comprising administering to the subject a therapeutically-effective amount of a dietary product, wherein the dietary product comprises at most about 0.5% (w/w) of cysteine or cystine, and wherein the dietary product comprises at least about 7.5% (w/w) of at least one essential amino acid selected from the group consisting of:
- methionine, histidine, isoleucine, leucine, lysine, phenylalanine, threonine, tryptophan, and valine, wherein the therapeutically-effective amount of the dietary product is from about 0.5 g/kg/day to about 1 g/kg/day,
- wherein the subject is undergoing a cancer therapy for the cancer,
- wherein the administering the dietary product to the subject increases efficacy of the cancer therapy in the subject by at least about 10% as compared to an efficacy of the cancer therapy in a comparable subject receiving the cancer therapy, but not the dietary product.
(canceled)
21-40. (canceled)
Dependencies are inferred from the claim text.