Prosthetic heart valve comprising a stent structure having a conical-convex inflow region and a linear cylindrical outflow region

A prosthetic heart valve, comprising:

• a stent structure that is configured to expand from a compressed state for transluminal delivery to a natural expanded state, the stent structure comprising a mesh structure that has an essentially tubular shape and that furthermore defines a circumference with contours, wherein the contours define a proximal inlet region, a distal outlet region, and an intermediate transition region, wherein the intermediate transition region connects the inlet region and outlet region to each another, and wherein the mesh structure comprises a plurality of closed cells that in the longitudinal direction of the prosthetic heart valve have varying cell sizes and cell configurations to define a plurality of cell patterns that vary in size between the proximal inlet region, the distal outlet region, and the intermediate transition region, and
• a valve arrangement that is arranged inside a lumen of the stent structure, wherein
• the cells in the inlet region are formed and arranged to define a conical-convex outer shape across the entire circumference of the inlet region,
• the cells in the outlet region are shaped and arranged to define a linear cylindrical outer shape across the entire circumference of the outlet region,
• two or more cells in the transition region are shaped and arranged for permitting a cell surface area of suitable size for free access to the coronary arteries, and
• the cells of the inlet region, outlet region, and transition region are configured differently from one another to create, when the stent structure is in the expanded state, a higher maximum radial force in the inlet region in direct comparison to a lower maximum radial force in the outlet region and in the transition region.