Systems and Methods for Cell Collection and Protection of Harvested Cells
AssigneePAVmed Inc.
InventorsLishan Aklog, Brian J. deGuzman, Richard Yazbeck, Michael Boutillette, Jessie Gifford
Life of this patent
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Abstract
Methods and systems for cell collection. Methods and systems include a collection mechanism being transformable between a collection state having an expanded diameter and a retrieval state where the diameter is less than that of the collection state and a conveyance mechanism having a distal end to which the collection mechanism is attached and designed to place the collection mechanism at a site of interest for cell collection. The Methods and systems also include an activation mechanism to transform the collection mechanism between the collection state and the retrieval state.
Claims29
A system for cell collection, the system comprising:
- a collection mechanism being transformable between a collection state having an expanded diameter and a retrieval state where the diameter is less than that of the collection state;
- a conveyance mechanism having a distal end to which the collection mechanism is attached, and designed to place the collection mechanism at a site of interest for cell collection;
- and
- an activation mechanism to transform the collection mechanism between the collection state and the retrieval state, and to permit the collection mechanism to move independent of the conveyance mechanism.
A cell collection device, the device comprising:
- a cell collection mechanism having a proximal end and a distal end, the cell collection mechanism being transformable between at least one of a navigation state, a collection state, and a retrieval state;
- and
- a conveyance mechanism having a proximal end and a distal end, the distal end of the conveyance mechanism coupled to the proximal end of the cell collection mechanism.
A method for cell collection, the method comprising:
- inserting a cell collection mechanism within a body in a navigation state, the cell collection mechanism being transformable between at least one of a navigation state, a collection state, and a retrieval state;
- navigating the cell collection mechanism to a target site for cell collection;
- activating an activation mechanism to transform of the cell collection mechanism between navigation state to the collection state;
- moving the cell collection mechanism at the cell collection site to gather cells on at least one surface of the cell collection mechanism;
- activating the activation mechanism to transform of the cell collection mechanism between the collection state and the retrieval state to protect the collected cells;
- and
- removing the cell collection mechanism.
A method for cell collection, the method comprising:
- inserting, into an esophagus, an expandable cell collection mechanism coupled to a conveyance mechanism;
- expanding the collection mechanism at a targeted site to permit contact between the collection mechanism and surrounding esophageal walls;
- moving the collection mechanism while maintaining contact with the esophageal walls to collect cells at the targeted site;
- and
- collapsing the collection mechanism.
Dependencies are inferred from the claim text.