Blood sampling system and method

A method for drawing and storing blood from a user for analysis with a system comprising a receptacle, a lancet device, a vacuum device, and a housing, the method comprising:

• engaging, with the receptacle, an area of skin of the user at a blood draw location;
• puncturing, with the lancet device, the skin of the user at the blood draw location, the lancet device being disposed within and movable within the receptacle;
• absorbing, with a blood storage substrate, blood from the punctured skin, wherein the blood storage substrate is disposed within the receptacle;
• reducing, with the vacuum device, a pressure within the receptacle (1) such that the skin at the blood draw location is drawn into the receptacle before the lancet device punctures the skin, and (2) to enhance blood flow while blood is drawn from the user;
• and
• storing, with the receptacle, blood drawn from the user,
• wherein the receptacle together with the lancet device and the vacuum device are each modular and removably coupled with the housing,
• the housing having an opening for removably receiving the receptacle with the lancet device therein, wherein a first end of the receptacle comprises an opening that is configured to engage the area of the skin and a second end of the receptacle is configured to be sealed to support reduced pressure in the receptacle, and
• wherein the vacuum device is separately removable from the housing relative to the receptacle.

A receptacle comprising:

• a first end and a second end, the second end being opposite the first end and being sealed to support reduced pressure in the receptacle, the first end of the receptacle being configured to engage an area of skin of a user at a blood draw location and store blood drawn from the user;
• a lancet device disposed within and movable therein between the first end and the second end thereof and configured to puncture the skin of the user at the blood draw location;
• a blood storage substrate in the receptacle and disposed at or near the first end thereof, the blood storage substrate being configured to absorb blood from the punctured skin, the blood storage substrate comprising a solid, liquid, or gel stabilization matrix,
• wherein the receptacle and the lancet device are modular and the lancet device being removable together with the receptacle.