Method for an analyte sensor cover-membrane preparation

A process for forming a sensing layer on a first electrode of an analyte sensor, comprising:

• i) providing an analyte sensor having a first electrode comprising a first electrode material;
• ii) reacting the first electrode with a functionalizing compound which comprises a first group which is reactive towards the first electrode material and a second group which is cross-linkable to thereby obtain a functionalized first electrode;
• iii) providing a polymer mixture comprising a mediator polymer which comprises at least one cross-linkable group, and a solvent;
• iv) contacting the functionalized first electrode obtained in step ii) with the polymer mixture provided in step iii) to obtain a coated functionalized first electrode;
• v) drying the coated functionalized first electrode obtained in step iv) to obtain a dried coated first electrode which is coated with the mediator polymer;
• and
• vi) curing the dried coated first electrode, whereby the second group of the functionalizing compound and the cross-linkable group of the mediator polymer are cross-linked to form the sensing layer on the first electrode of the analyte sensor.