Speckle-based image distortion correction for laser scanning microscopy
AssigneeThe General Hospital Corporation
InventorsGuillermo J. Tearney, Jiheun Ryu
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Abstract
A method of correcting distortion of an image, including: analyzing, by a processor, an image segment of the image to identify a speckle artifact, the image segment being obtained from a scanning imaging device; determining, by the processor, an aspect ratio of a shape of the speckle artifact; determining, by the processor, a correction factor for the shape of the speckle artifact based on the aspect ratio; and adjusting, by the processor, a dimension of the image segment based on the correction factor.
Claims34
A method of correcting distortion of an image, comprising:
- analyzing, by a processor, an image segment of the image to identify a speckle artifact,
- the image segment being obtained from a scanning imaging device;
- determining, by the processor, an aspect ratio of a shape of the speckle artifact;
- determining, by the processor, a correction factor for the shape of the speckle artifact based on the aspect ratio;
- and
- adjusting, by the processor, a dimension of the image segment based on the correction factor.
An apparatus for correcting distortion of an image, comprising:
- a processor;
- and
- a memory in communication with the processor having stored thereon a set of instructions which, when executed by the processor, cause the processor to:
- analyze an image segment of the image to identify a speckle artifact,
- the image segment being obtained from a scanning imaging device,
- determine an aspect ratio of a shape of the speckle artifact,
- determine a correction factor for the shape of the speckle artifact based on the aspect ratio, and
- adjust a dimension of the image segment based on the correction factor.
A method of distortion correction, the method comprising:
- providing an image;
- dividing the image into a plurality of substantially parallel strips, each strip extending in a first direction;
- dividing each strip into a plurality of substrips along a second direction substantially perpendicular to the first direction;
- analyzing each of the plurality of substrips to locate at least one locally bright feature;
- adjusting at least a portion of each substrip to urge the at least one locally bright feature toward a predetermined shape to create a corrected substrip;
- reassembling the plurality of corrected substrips into a corrected strip;
- and
- reassembling the plurality of corrected strips into a corrected image.
An apparatus for correcting distortion of an image, comprising:
- a scanning imaging device including a coherent light source,
- the scanning imaging device being configured to obtain an image of a sample;
- a processor in communication with the scanning imaging device;
- and
- a memory in communication with the processor having stored thereon a set of instructions which, when executed by the processor, cause the processor to:
- analyze an image segment of the image to identify a speckle artifact,
- determine an aspect ratio of a shape of the speckle artifact,
- determine a correction factor for the shape of the speckle artifact based on the aspect ratio, and
- adjust a dimension of the image segment based on the correction factor.
Dependencies are inferred from the claim text.