Phage derived antimicrobial activities
AssigneeBactoclear Holdings PTE. Ltd
InventorsSriram Padmanabhan, Vivek Daniel Paul, R. Sanjeev Saravanan, Bharathi Sriram
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Abstract
The present invention provides methods and compositions to reduce growth of microbial colonies, including infections, and includes therapeutic compositions, methods for treatment of infections, and methods for identifying additional such compositions.
Claims18
A chimeric Tail Associated Muralytic Enzyme (TAME) polypeptide, wherein the chimeric TAME polypeptide comprises a muralytic domain (MD) and a heterologous cell binding domain (CBD) that binds to a target bacterium, wherein the target bacterium exhibits reduced or no growth after being contacted with the chimeric TAME polypeptide.
18-43. (canceled)
Dependencies are inferred from the claim text.