# US 2022/0032284 A1 · Integrated cartridge > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 2022/0032284 A1 - Document ID: US20220032284A1 - Status: Published application - Kind: A1 - Application number: 17/278,846 - Filed: 2019-08-07 - Published: 2022-02-03 - Earliest claimed: 2018-10-11 - Assignees: LG Chem, Ltd. - Applicants: LG Chem, Ltd. - Inventors: Chang Ju PARK; Sang Hun LEE; Dong Hyun KIM; Se Ryun KIM; Jae Hoon OH; Ji Hyun PARK - Web page: https://patentgrep.com/patent/US20220032284A1 ## CPC - B01L 3/502: {with fluid transport, e.g. in multi-compartment structures} - B01L 7/52: {with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples} - B01L 2200/0647: Handling flowable solids, e.g. microscopic beads, cells, particles - B01L 2200/0684: Venting, avoiding backpressure, avoid gas bubbles - B01L 2200/10: Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept - B01L 2200/141: Preventing contamination, tampering - B01L 2200/16: Reagents, handling or storing thereof - B01L 2300/0832: cylindrical, tube shaped - B01L 2300/0861: Configuration of multiple channels and/or chambers in a single devices - B01L 2300/0864: comprising only one inlet and multiple receiving wells, e.g. for separation, splitting - B01L 2300/161: Control and use of surface tension forces, e.g. hydrophobic, hydrophilic - B01L 2400/0406: capillary forces - B01L 2400/0644: rotary valves - B01L 2400/0688: surface tension valves, capillary stop, capillary break - B01L: CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE ## Abstract According to one aspect of the present invention, provided is an integrated cartridge including a pre-processing part configured to pre-process a sample, an elution part configured to elute an effective component from the sample that is pre-processed in the pre-processing part, and an accommodation part configured to accommodate the effective component. The accommodation part includes a supply unit configured to supply the effective component discharged from the elution part, a storage unit which stores and amplifies the effective component supplied from the supply unit and in which a pipe is provided, and an air discharge unit configured to discharge air existing in the pipe of the storage unit to the outside. ## Claims ### Claim 1 An integrated cartridge comprising: a pre-processing part configured to pre-process a sample; an elution part configured to elute an effective component from the pre-processed sample; and an accommodation part configured to accommodate the effective component, wherein the accommodation part comprises: a supply unit configured to supply the effective component discharged from the elution part; a storage unit configured to store and amplify the effective component supplied from the supply unit and containing at least one pipe therein and an air discharge unit configured to discharge air existing in the pipe of the storage unit to the outside. ### Claim 2 (depends on 1) The integrated cartridge of claim 1, wherein at least one hole is formed in each of the supply unit and the air discharge unit, input and output holes are respectively defined in each end of the pipe of the storage unit, and are configure to respectively face holes formed in the supply unit and the air discharge unit, and when the hole formed in the supply unit matches the input hole, the effective component is supplied into the pipe. ### Claim 3 (depends on 2) The integrated cartridge of claim 2, wherein when the effective component is supplied into the pipe, the hole formed in the air discharge unit and the output hole match each other to discharge the air existing in the pipe to the outside through the air discharge unit. ### Claim 4 (depends on 2) The integrated cartridge of claim 2, wherein the effective component is transferred in the pipe of the storage unit by capillary force. ### Claim 5 (depends on 4) The integrated cartridge of claim 4, wherein a coating layer made of a hydrophilic material is disposed on an inner wall of the pipe of the storage unit and the coating layer made of a hydrophilic material generates the capillary force. ### Claim 6 (depends on 4) The integrated cartridge of claim 4, wherein a coating layer made of a hydrophilic material is disposed on an inner wall of the hole of the supply unit and the coating layer made of a hydrophilic material generates the capillary force. ### Claim 7 (depends on 4) The integrated cartridge of claim 4, wherein a coating layer made of a hydrophobic material is disposed on an inner wall of the hole of the air discharge unit and the coating layer made of a hydrophobic material suppresses generation of the capillary force. ### Claim 8 (depends on 2) The integrated cartridge of claim 2, wherein one hole is formed in the supply unit, a plurality of pipes are disposed in the storage unit, and the supply unit is provided to be rotatable so as to allow the hole of the supply unit to match each of the input holes of the plurality of pipes. ### Claim 9 (depends on 2) The integrated cartridge of claim 2, wherein a plurality of holes are formed in the air discharge unit, a plurality of pipes are disposed in the storage unit to provide a plurality of output holes, and the air discharge unit is provided to be rotatable so as to allow one of the holes of the air discharge unit to match one of the plurality of output holes. ### Claim 10 (depends on 9) The integrated cartridge of claim 9, wherein the air discharge unit has the same number of holes as the number of the output holes defined in the plurality of pipes. ### Claim 11 (depends on 1) The integrated cartridge of claim 1, wherein the accommodation part is provided below the elution part so that the effective component discharged from the elution part is supplied to the supply unit due to gravity or capillary force. ### Claim 12 (depends on 1) The integrated cartridge of claim 1, wherein the effective component eluted in the elution part contains water to form a fluid containing an effective component. ### Claim 13 (depends on 1) The integrated cartridge of claim 1, wherein the effective component is a nucleic acid. ### Claim 14 (depends on 1) The integrated cartridge of claim 1, wherein the sample comprises a genetic material containing a nucleic acid.