# US 2022/0031986 A1 · Respiratory rate measurement device

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- Number: US 2022/0031986 A1
- Document ID: US20220031986A1
- Status: Published application
- Kind: A1
- Application number: 17/279,215
- Filed: 2019-09-27
- Published: 2022-02-03
- Earliest claimed: 2018-09-28
- Assignees: Teijin Pharma Limited
- Applicants: Teijin Pharma Limited
- Inventors: Yuki YAMAURA; Yuta MORISHITA; Akira YOSHIZAWA
- Web page: https://patentgrep.com/patent/US20220031986A1

## CPC

- A61M 16/026: {specially adapted for predicting, e.g. for determining an information representative of a flow limitation during a ventilation cycle by using a root square technique or a regression analysis}
- A61B 5/0816: {Measuring devices for examining respiratory frequency (measuring frequency of electric signals G01R23/00)}
- A61B 5/087: Measuring breath flow
- A61B 5/7246: {using correlation, e.g. template matching or determination of similarity}
- A61M 16/024: {including calculation means, e.g. using a processor}
- A61M 16/101: {using an oxygen concentrator}
- B01D 53/047: Pressure swing adsorption
- A61B 2505/07: Home care
- A61M 16/0063: {Compressors}
- A61M 16/0672: {Nasal cannula assemblies for oxygen therapy}
- A61M 16/16: Devices to humidify the respiration air {(A61M16/1045 takes precedence)}
- A61M 16/202: {electrically actuated}
- A61M 2016/0021: {with a proportional output signal, e.g. from a thermistor}
- A61M 2016/0027: {pressure meter}
- A61M 2016/0039: {in the inspiratory circuit}
- A61M 2202/0208: Oxygen
- A61M 2205/3331: Pressure; Flow
- A61M 2205/502: User interfaces, e.g. screens or keyboards
- A61M 2230/42: Rate
- B01D 2256/12: Oxygen
- B01D 2259/40007: Controlling pressure or temperature swing adsorption
- B01D 2259/40009: using sensors or gas analysers
- B01D 2259/4533: for medical purposes
- A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)}
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)
- B01D: SEPARATION (separating solids from solids by wet methods B03B, B03D; by pneumatic jigs or tables B03B; by other dry methods B07; magnetic or electrostatic separation of solid materials from solid materials or fluids, separation by high-voltage electric fields B03C; centrifuges, vortex apparatus B04; presses per se for squeezing-out liquid from liquid-containing material B30B9/02; treatment of water C02F, e.g. softening by ion-exchange C02F1/42; {arrangements of air intake cleaners in gas turbine plants F02C7/05} ; arrangements or mounting of filters in air-conditioning, air-humidification or ventilation F24F13/28)

## Abstract

Provided is a respiratory rate measurement device (4), the respiratory rate measurement device (4) including a detection unit (6) that detects an in-tube pressure and/or an in-tube gas flow rate in a tube (2) supplying concentrated oxygen gas to a patient from a pressure swing adsorption oxygen concentration device (1) connected to the patient and concentrating oxygen in the air by periodically repeating pressurization and depressurization, and outputs pressure data and/or gas flow rate data, an arithmetic operation unit (722) that extracts patient respiratory information data, based on the pressure data and/or the gas flow rate data, and an estimation unit (723) that estimates a respiratory rate per predetermined time, based on the patient respiratory information data, wherein the estimation unit (723) estimates the respiratory rate using, as a respiratory interval, a time Δt in which the autocorrelation coefficient takes a peak.

## Claims

### Claim 1

A respiratory rate measurement device comprising:
a detection unit that detects an in-tube pressure and/or an in-tube gas flow rate in a tube supplying concentrated oxygen gas to a patient from a pressure swing adsorption oxygen concentration device connected to the patient and concentrating oxygen in the air by periodically repeating pressurization and depressurization, and outputs pressure data and/or gas flow rate data;
an arithmetic operation unit that extracts patient respiratory information data, based on the pressure data and/or the gas flow rate data; and
an estimation unit that estimates a respiratory rate per predetermined time, based on the patient respiratory information data,
wherein the estimation unit calculates an autocorrelation coefficient between the patient respiratory information data and data shifted from the patient respiratory information data by a time Δt, while changing the time Δt, and estimates the respiratory rate using, as a respiratory interval, a time Δt in which the autocorrelation coefficient takes a peak.

### Claim 2 (depends on 1)

The respiratory rate measurement device according to claim 1, wherein the estimation unit estimates the respiratory rate, using a waveform indicating the patient respiratory information data of at least 10 seconds.

### Claim 3 (depends on 1)

The respiratory rate measurement device according to claim 1, wherein the estimation unit uses a peak of the autocorrelation coefficient exceeding a predetermined threshold to estimate the respiratory rate.

### Claim 4 (depends on 3)

The respiratory rate measurement device according to claim 3, wherein the threshold takes a value of 0.3 to 0.7.

### Claim 5 (depends on 1)

The respiratory rate measurement device according to claim 1, wherein information indicating that computation has been impossible is output when a peak of the autocorrelation coefficient exceeding the predetermined threshold fails to be obtained.

### Claim 6 (depends on 1)

The respiratory rate measurement device according to claim 1, wherein the arithmetic operation unit estimates variation value data representing a periodical pressure change and/or flow rate change of the concentrated oxygen gas occurring upon an operation of an oxygen concentration device, based on the pressure data and/or the gas flow rate data, and extracts the patient respiratory information data by removing the variation value data from the pressure data and/or the gas flow rate data.

### Claim 7 (depends on 1)

The respiratory rate measurement device according to claim 1, further comprising a storage unit that stores the variation value data measured in advance,
wherein the arithmetic operation unit extracts the patient respiratory information data by removing the variation value data from the pressure data and/or the gas flow rate data.