Bioresorbable, implantable device having controlled drug delivery
OwnerJohn James Scanlon, Catherine Ann Scanloninventors
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Abstract
A bioresorbable, implantable device having controlled drug delivery is disclosed herein. The bioresorbable, implantable device is configured as a film, a roll, a tube, and a stent. The bioresorbable, implantable device is configured to release an active ingredient (the “drug”) from the bioresorbable, implantable device when the bioresorbable, implantable device is implanted within a body. The bioresorbable, implantable device is configured to control the onset of the release of the drug, the sequence of drug delivery, and the duration of drug delivery by embedding the drug within at least one therapeutic layer positioned within bioresorbable, implantable device.
Claims23
A bioresorbable implantable device comprising:
- an implantable film comprising a film width, a film length, two film major surfaces, four film minor surfaces and a film thickness comprising at least one bioresorbable material,
- a removable release media, and
- a temporary bond, excluding a separate adhesive, disposed between the release media and at least one film major surface of said film.
A bioresorbable implantable device comprising:
- a film comprising a film width, a film length, two film major surfaces, four film minor surfaces and a film thickness comprising at least one bioresorbable material disposed within an active ingredient free area and at least one bioresorbable material and at least one dry active ingredient disposed within an active ingredient storage area,
- a roll comprising said film including a beginning of the roll, an end of the roll, a roll inner diameter, a roll outer diameter, a roll length, a roll passageway, a roll central axis and a roll thickness comprising multiple said film thicknesses in spiral cross section perpendicular to the roll central axis, wherein said beginning of the roll is disposed inside the roll passageway and the end of the roll disposed outside the roll,
- a bond, comprising at least one part said bioresorbable material, disposed between the adjacent film thicknesses within the roll thickness, the roll comprising the bonded film thicknesses transformable into a tube including a tube outer surface, a tube inner surface, a tube length, a tube central axis and a tube thickness and
- at least one opening in a pattern through the tube thickness generally perpendicular to the tube central axis and at least one strut adjacent to the opening having a strut thickness comprising at least one part said bioresorbable material another part comprising said bioresorbable material and said active ingredient, the tube transformable into a stent including a stent outer surface, a stent inner surface, a stent length, a stent cutting surface, a stent central axis and a stent thickness.
A bioresorbable implantable device comprising:
- a film comprising a film width, a film length, two film major surfaces, four film minor surfaces and a film thickness comprising at least one bioresorbable material, and at least one coating disposed on at least one part of at least one film major surface,
- a roll comprising said film including a beginning of the roll, an end of the roll, a roll inner diameter, a roll outer diameter, a roll length, a roll passageway, a roll central axis and a roll thickness comprising multiple said film thicknesses in spiral cross section perpendicular to the roll central axis, wherein said beginning of the roll is disposed inside the roll passageway and the end of the roll disposed outside the roll,
- a bond, comprising at least one part said bioresorbable material, disposed between the adjacent film thicknesses within the roll thickness, the roll comprising the bonded film thicknesses transformable into a tube including a tube outer surface, a tube inner surface, a tube length, a tube central axis and a tube thickness and
- at least one opening in a pattern through the tube thickness generally perpendicular to the tube central axis and at least one strut adjacent to the opening having a strut thickness comprising at least one part said bioresorbable material and one part said coating, the tube transformable into a stent including a stent outer surface, a stent inner surface, a stent length, a stent cutting surface, a stent central axis and a stent thickness.
The coating of film 21 includes at least one active ingredient.
Dependencies are inferred from the claim text.