Method for manufacturing surface-enhanced raman scattering-based substrate for detecting target substance, substrate manufactured thereby for detecting target substance, and method for detecting target substance by using same substrate
AssigneeExopert Corporation
InventorsYeon Ho CHOI, Hyun Ku SHIN
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Abstract
The present disclosure relates to a method for manufacturing a surface-enhanced Raman scattering (SERS)-based substrate for detecting a target substance, by which the surface of a target substance can be easily coated with metal nanoparticles through centrifugation, a substrate for detecting a target substance manufactured thereby, and a method for detecting a target substance using the same.
Claims17
A method for manufacturing a surface-enhanced Raman scattering (SERS)-based substrate for detecting a target substance, comprising:
- a step of forming a primary capture structure with a target substance and a bioreceptor bound by immersing a bioreceptor-attached substrate in a sample solution comprising a target substance;
- a step of disposing the substrate with the primary capture structure formed in a centrifuge and adding a solution comprising metal nanoparticles into the centrifuge;
- and
- a step of forming a secondary capture structure coating the metal nanoparticles on the surface of the target substance by operating the centrifuge.
A surface-enhanced Raman scattering (SERS)-based substrate for detecting a target substance, comprising:
- a bioreceptor-attached substrate;
- a target substance captured by the bioreceptor;
- metal nanoparticles capping the target substance;
- and
- a Raman dye attached to the metal nanoparticles,
- wherein the target substance is sandwiched between the bioreceptor and the metal nanoparticles to form a capture structure.
Dependencies are inferred from the claim text.