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US 2022/0025338 A1Published application
Composition comprising nc886 for improving oncolytic virus activity or production
AssigneeNational Cancer Center
InventorsYongsun LEE, Inhoo KIM, Seunghil SHIN, Sangjin LEE, Yeonsu LEE
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Abstract
The present invention relates to a composition for enhancing oncolytic virus activity which comprises nc886, and a composition for enhancing virus production which comprises the same.
Claims12
-14. (canceled)
A composition for enhancing virus production, comprising:
- nc886 or an activator thereof.
A method for enhancing virus production, comprising:
- a step of adding nc886 or an activator thereof.
A composition for enhancing activity of an oncolytic viral therapeutic agent, comprising:
- nc886 or an activator thereof.
A method for preventing or treating cancer,
- the method comprising administering a pharmaceutical composition comprising:
- nc886 or an activator thereof;
- and
- an oncolytic viral therapeutic agent.
1 more element
A method for screening a candidate for treatment of a viral infection, comprising steps of:
- (a) contacting an nc886-expressing cell with a test substance;
- (b) analyzing an expression level of nc886 in the cell;
- and
- (c) in a case where the test substance causes decreased expression of nc886-determining the test substance as a candidate for treatment of a viral infection.
1 more element
Dependencies are inferred from the claim text.