Robust self-regeneratable stiff living materials
AssigneesNortheastern University Center for Research Innovation, Northeastern Univ., President and Fellows of Harvard College
InventorsAvinash M. Basavanna, Anna Duraj-Thatte, Neel S. Joshi
Life of this patent
Estimating the term…
Abstract
Disclosed are biomaterials, including engineered living materials (ELMs), comprising a plurality of microbial cells, wherein the material has a Young's Modulus of at least 5 Gpa; and methods of fabricating said biomaterials.
Claims58
An engineered living material (ELM), comprising a plurality of microbial cells, wherein the ELM has a Young's Modulus of at least 5 Gpa.
(canceled)
(canceled)
-9. (canceled)
(canceled)
(canceled)
(canceled)
-22. (canceled)
A method of fabricating an ELM, wherein the ELM has a Young's Modulus of at least 5 Gpa, comprising proliferating a plurality of engineered xerotolerant microbial cells to produce a population of engineered living xerotolerant microbial cells;
- isolating and casting said living xerotolerant microbial cells onto a substrate;
- and allowing the isolated cells to dry;
- thereby forming an ELM.
(canceled)
(canceled)
(canceled)
(canceled)
-37. (canceled)
-45. (canceled)
(canceled)
An engineered biomaterial, comprising a plurality of microbial cells, wherein
- the biomaterial does not comprise extracellular components,
- the biomaterial does not comprise living microbial cells, and
- the biomaterial has a Young's Modulus of at least 5 Gpa.
(canceled)
-54. (canceled)
-62. (canceled)
-65. (canceled)
(canceled)
A method of fabricating a biomaterial, wherein the biomaterial has a Young's Modulus of at least 5 Gpa, comprising proliferating a plurality of engineered xerotolerant microbial cells to produce a population of engineered living xerotolerant microbial cells;
- isolating and casting said living xerotolerant microbial cells onto a substrate;
- and desiccating the isolated cells;
- thereby forming the biomaterial.
(canceled)
-73. (canceled)
-76. (canceled)
(canceled)
(canceled)
-83. (canceled)
(canceled)
Dependencies are inferred from the claim text.