Pyrrolo - dipyridine compounds
AssigneeOsteoQC Inc.
InventorsDebra ELLIES, F. Scott Kimball, Robert N. Young
Life of this patent
Estimating the term…
Abstract
In one aspect, the invention provides compounds of Formula I Formula Ia, Formula Ib, Formula Ic, and Formula Id and salts, hydrates and isomers thereof. In another aspect, the invention provides a method of promoting bone formation in a subject in need thereof by administering to the subject a therapeutically effective amount of a compound of Formula I, Formula Ia, Formula Ib, Formula Ic, or Formula Id. The present invention also provides orthopedic and periodontal devices, as well as methods for the treatment of renal disease, diabetes bone loss, and cancer, using a compound of Formula I, Formula Ia, Formula Ib, Formula Ic, or Formula Id.
Claims47
-49. (canceled)
A medical device comprising a structural support, wherein an implantable portion of the structural support is adapted to be permanently implanted within a subject, wherein the implantable portion is attached to a bone, the structural support bears at least a partial external or internal coating comprising a compound selected from the group consisting of
- or a salt or hydrate thereof.
A method of promoting bone formation in a subject in need thereof, comprising administering to the subject a therapeutically effective of a compound selected from the group consisting of
- or a salt or hydrate thereof, thereby promoting bone formation in the subject.
A method of treating diabetes, comprising administering to the subject a therapeutically effective of a compound selected from the group consisting of
- or a salt or hydrate thereof.
Dependencies are inferred from the claim text.