US 2022/0024905 A1 · CRYSTALLINE FORM OF PROPANAMIDE DERIVATIVE AND PREPARATION METHOD THEREFOR

Abstract

The present invention relates to crystal form A of a propionamide derivative and a preparation method therefor. The crystal form A of the compound of formula (1) obtained in the present invention has good crystalline stability and chemical stability, and can be better used in clinical treatment.

Claims18

Dependent claims

Crystal Form A of a compound of formula (1), wherein

the Crystal Form A has characteristic peaks at 4.46, 11.30, 13.59, 18.17, 21.38, 22.03, 25.89 in the X-ray powder diffraction pattern obtained by Cu-Kα radiation and represented by diffraction angle 2θ angle, wherein the error range of each characteristic peak 2θ is ±0.2,

Dependencies are inferred from the claim text.

Facts

Application

17/309,542Filed 9 Dec 2019

Priority

CN 201811499965.47 Dec 2018

Published

27 Jan 2022

Term ends

Not estimatedThe source records don’t support an estimate.

Classification7 codes

C07D 413/12
Containing two hetero rings: linked by a chain containing hetero atoms as chain links
A61P 25/18
Drugs for disorders of the nervous system: antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
C07D 413/14
Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms:…
C07B 2200/13
Indexing scheme relating to specific properties of organic compounds: crystalline forms, e.g. polymorphs

Abstract

Claims18

Dependent claims

Crystal Form A of a compound of formula (1), wherein

the Crystal Form A has characteristic peaks at 4.46, 11.30, 13.59, 18.17, 21.38, 22.03, 25.89 in the X-ray powder diffraction pattern obtained by Cu-Kα radiation and represented by diffraction angle 2θ angle, wherein the error range of each characteristic peak 2θ is ±0.2,

Dependencies are inferred from the claim text.

Facts

Application

17/309,542Filed 9 Dec 2019

Priority

CN 201811499965.47 Dec 2018

Published

27 Jan 2022

Term ends

Not estimatedThe source records don’t support an estimate.

Classification7 codes

C07D 413/12
Containing two hetero rings: linked by a chain containing hetero atoms as chain links
A61P 25/18
Drugs for disorders of the nervous system: antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
C07D 413/14
Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms:…
C07B 2200/13
Indexing scheme relating to specific properties of organic compounds: crystalline forms, e.g. polymorphs

Crystalline form of propanamide derivative and preparation method therefor

Life of this patent

Abstract

Claims18

Crystalline form of propanamide derivative and preparation method therefor

Life of this patent

Abstract

Claims18