Process route of compound of formula (iv), crystal form and preparation method therefor
AssigneeShandong Danhong Pharmaceutical Co., Ltd.
InventorsZhi LUO, Xiaolin LI, Yaxun YANG, Lele YANG, Peng LI, Haiying HE, Jian LI, Shuhui CHEN
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Abstract
Disclosed are a process route of a compound of a compound of formula (IV), a crystal form and a preparation method therefor. Also disclosed is an application of the crystal form in preparation of drugs for treating diseases associated with SSAO.
Claims22
A crystal form A of a compound of formula (IV), wherein the X-ray powder diffraction (XRPD) pattern thereof has characteristic diffraction peaks at the following 2θ angles:
- 9.05±0.2°, 12.34±0.2°, and 22.52±0.2°,
4-7. (canceled)
10-11. (canceled)
A crystal form B of compound of formula (IV), wherein the X-ray powder diffraction (XRPD) pattern thereof has characteristic diffraction peaks at the following 2θ angles:
- 11.27±0.2°, 21.44±0.2°, 22.32±0.2°,
16-19. (canceled)
22-23. (canceled)
(canceled)
A preparation method of a compound of formula (IV),
- which comprises the following steps:
- wherein,
- solvent a is acetic acid;
- reagent b is hydrochloric acid.
28-29. (canceled)
Dependencies are inferred from the claim text.