Nanosecond pulsed electric field system
AssigneePulse Biosciences, Inc.
InventorsKenneth R. KRIEG, Gregory P. SCHAADT, Chaofeng HUANG
Life of this patent
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Abstract
Described herein are apparatuses (e.g., systems and devices) and methods of delivering nanosecond pulsed electrical fields (nsPEF). In particular, these apparatuses and methods may provide enhanced safety and robust operation over even very short (e.g., nanosecond and sub-nanosecond pulses) and high voltage pulsing; these benefits may be accomplished by multi-functional isolation of various subsystems and components of the apparatus, even including the low-voltage, control and command portions of the apparatus with extremely low capacitance, high voltage isolation.
Claims26
A system for delivering nanosecond pulsed electrical energy, the system comprising:
- a console including:
- a treatment controller,
- a nanosecond pulse generator configured to provide at least a high voltage pulsed output, and
- a console-handpiece isolation board configured to receive the high voltage pulsed output from the nanosecond pulse generator;
- and
- a handpiece subsystem comprising:
- a handpiece configured to deliver the high voltage pulsed output from a treatment tip;
- a handpiece cable coupled to the handpiece and coupled or configured to couple to the console-handpiece isolation board,
- wherein the console-handpiece isolation board couples the high voltage pulsed output through a multi-functional isolation connection with the handpiece cable.
A system for delivering nanosecond pulsed electrical energy, the system comprising:
- a treatment controller receiving input from one or more user interfaces;
- a nanosecond pulse generator;
- a handpiece subsystem comprising a handpiece for delivering pulses from the nanosecond pulse generator;
- and
- an interface board comprising a plurality of electromagnetic interference (EMI)-filtered, transient protected and high-voltage isolation barriers, wherein each of the treatment controller, the nanosecond pulse generator and the handpiece subsystem are coupled to the interface board so that all power and communications between the nanosecond pulse generator and the handpiece subsystem or treatment controller passes through the EMI-filtered, transient protected and high-voltage isolation barriers of the interface board.
A system for delivering nanosecond pulsed electrical energy, the system comprising:
- a treatment controller receiving input from one or more user interfaces;
- a nanosecond pulse generator, wherein the nanosecond pulse generator comprises
- a system interconnect circuit,
- a low voltage pulse triggering and timing circuit, and
- a pulse output circuit,
- wherein the system interconnect circuit, the low voltage pulse triggering and timing circuit and the pulse output circuit are each electrically isolated from each other by one or more multi-function isolation connections having a capacitance of 20 pF or less;
- a handpiece subsystem for delivering pulses from the nanosecond pulse generator;
- and
- an interface board comprising a plurality of electromagnetic interference (EMI)-filtered, transient protected and high-voltage isolation barriers, wherein each of the treatment controller, the nanosecond pulse generator and the handpiece subsystem are all coupled to the interface board so that all power and communications between the nanosecond pulse generator and the handpiece subsystem or treatment controller passes through the EMI-filtered, transient protected and high-voltage isolation barriers of the interface board.
A method of delivering nanosecond pulsed electrical energy, the method comprising;
- providing system power and pulse generator power from a system power supply to an interface board comprising one or more high-voltage isolation barriers, wherein the interface board is connected to a nanosecond pulse generator;
- receiving user input from one or more user interfaces through a treatment controller coupled to the interface board;
- transmitting all communications to and from the nanosecond pulse generator through the one or more high-voltage isolation barriers of the interface board;
- and
- delivering a high voltage pulsed output from the nanosecond pulse generator to a handpiece of the handpiece subassembly through the one or more high-voltage isolation barriers of the interface board, wherein the high voltage pulsed output is based on the user input.
Dependencies are inferred from the claim text.