Kit for inhaled chemotherapy, and treatment of lung cancer with said kit
AssigneeUniversite Libre de Bruxelles
InventorsKarim Amighi, Nathalie Wauthoz, Rémi Rosière
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Abstract
A kit for an inhaled chemotherapy includes a series of single hermetically packaged therapeutic doses of a dry powder for inhalation. The dry powder includes at least one anti-neoplastic agent chosen from the group that includes platinum drugs with a lipid matrix and a PEGylated excipient and a series of disposable dry powder inhaler devices. The use and a method of treatment of cancer lungs with said kit is also described.
Claims36
A kit for an inhaled chemotherapy comprising:
- a) a series of single hermetically packaged therapeutic doses of a dry powder for inhalation, the dry powder containing at least one anti-neoplastic agent with a lipid matrix and optionally one or more excipient, such as a PEGylated excipient and/or a carrier;
- b) a series of disposable dry powder inhaler devices, wherein
- i) each single hermetically packaged therapeutic dose having a close state and an open state,
- ii) each disposable dry powder inhaler device having a close position and optionally an open position,
- iii) each single hermetically packaged therapeutic dose being provided for being accommodated in said close state in one disposable dry powder inhaler device of said series of disposable dry powder inhaler devices, and
- iv) each single disposable dry powder inhaler device is provided to be in said close position before or once each single hermetically packaged therapeutic dose become in said open state.
A therapeutic treatment against lung cancer comprising the steps of administering at least one inhaled chemotherapy in a polytherapy comprising at least one therapy chosen from the group consisting of intravenous infusion or oral chemotherapy, immunotherapy, targeted therapy, hormonotherapy, tumor ablative surgery, ablative surgery for removing a part of or a full organ bearing a tumor, a curative surgery, a radiotherapy and their combination said at least one inhaled chemotherapy being an additional therapy.
Dependencies are inferred from the claim text.