Devices and systems for delivery of combination therapies
AssigneeBristol-Myers Squibb Company
InventorsMartin John McLoughlin, Stephen Lawrence Zieminski, Chester Larrow, Mariano Mumpower
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Abstract
In one aspect, the subject invention is directed to a method of preparing a combinatorial drug delivery device based on a predetermined selection of drug components. The method includes: preparing a plurality of containers, each accommodating one of the selected drug components; coupling the containers to a common outlet so that the drug components may be extracted from the containers and dispensed through the common outlet; and, applying negative pressure to extract the drug components from the containers and urge the drug components towards the common outlet.
Claims30
A method of preparing a combinatorial drug delivery device based on a predetermined selection of drug components, the method comprising:
- preparing a plurality of discrete containers, each accommodating one of the selected drug components;
- coupling the containers to a common outlet, the common outlet being in communication with each of the coupled containers through a common flow path so that the drug components may be extracted from the coupled containers and dispensed through the common outlet;
- and,
- applying negative pressure to the common outlet, externally of the coupled containers, to extract the drug components from the containers and urge the drug components towards the common outlet.
A combinatorial drug delivery device for delivering a drug combination based on a predetermined selection of drug components, the device comprising:
- a plurality of discrete containers, each accommodating one of the selected drug components;
- a body having a common outlet, wherein the containers are configured to couple to the body so that the drug components may be extracted from the containers and dispensed through the common outlet, the containers being accessible externally of the body;
- and,
- a source of negative pressure mounted to the body, the source of negative pressure being configured to apply negative pressure to the common outlet, externally of the coupled containers, to extract the drug components from the coupled containers and urge the drug components towards the common outlet.
A combinatorial drug delivery device for delivering a drug combination based on a predetermined selection of drug components, the device comprising:
- a plurality of containers, each accommodating one of the selected drug components;
- a plurality of housings, each formed to accommodate one of the containers, wherein each of the housings includes a spike for accessing the drug component of the container located in the associated housing and a fluid path for the drug component;
- a common outlet;
- and,
- a source of negative pressure configured to extract the drug components from the containers and urge the drug components towards the common outlet.
Dependencies are inferred from the claim text.