Systems and methods for collection of increased volumes of igg during plasma collection procedures
AssigneeFenwal, Inc.
InventorJames Madsen
Life of this patent
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Abstract
A plasmapheresis system and a method for operating a plasmapheresis system are provided by which the reservoir for the concentrated red blood cells (RCC) has a first chamber for receiving anticoagulant used for priming the separator and purging the system of air prior to the initial draw cycle and a second chamber for receiving separated red blood cells. Because the entire volume of second chamber of the RCC reservoir may now receive separated red blood cells and no AC prime volume, a greater amount of whole blood may be processed in the first draw cycle, thus resulting in a greater total volume of Immunoglobulin G (IgG) being collected during the plasmapheresis procedure.
Claims15
A method for performing a plasmapheresis procedure having a priming phase, at least one collection phase, and at least on reinfusion phase so as to maximize a volume of whole blood processed during a first draw phase comprising:
- a) providing a disposable fluid flow set having a plurality of tubing segments in fluid communication with a reservoir comprising a first chamber into which priming fluid is flowed during the priming phase and a second chamber into which a cell fraction comprising separated blood cells is flowed during the collection phase and from which the separated blood cells are flowed during the reinfusion phase;
- b) introducing a priming fluid into the disposable fluid flow set;
- c) flowing spent priming fluid into the first chamber of the reservoir;
- and
- d) occluding one or more of the tubing segments to prevent flow into or out from the first chamber.
A disposable fluid flow set for an apheresis system comprising:
- e) a separator;
- f) a first tubing segment connected to an outlet of the separator;
- g) a second tubing segment;
- and
- h) a reservoir comprising first and second internal chambers, each having a first port in fluid communication with the first tubing segment and a second port in fluid communication with the second tubing segment.
Dependencies are inferred from the claim text.