Immunogenic composition, use and method of treatment
AssigneesGlaxosmithkline Biologicals SA, GlaxoSmithKline Intellectual Property Development Limited
InventorsCatherine COHET, Jeanne-Marie Josephine DEVASTER, David MAYHEW, Bruce MILLER, Ruth TAL-SINGER, Vincent WEYNANTS, Thomas WILKINSON
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Abstract
The present invention relates to immunogenic compositions comprising an immunogenic polypeptide from Haemophilus influenzae or an immunogenic fragment thereof and/or an immunogenic polypeptide from Moraxella catarrhalis or an immunogenic fragment thereof, for use in the treatment or prevention of a recurrence of an acute exacerbation of chronic obstructive pulmonary disease (AECOPD) resulting from a bacterial infection in a subject.
Claims22
1-40. (canceled)
A combination therapy comprising:
- (i) one or more therapeutic agents selected from the group consisting of beta2-agonists, anticholinergics, methylxanthines, phosphodiesterase-4 (PDE-4) inhibitors and inhaled corticosteroids;
- and
- (ii) an immunogenic composition comprising an immunogenic polypeptide from Haemophilus influenzae or an immunogenic fragment thereof and/or an immunogenic polypeptide from Moraxella catarrhalis or an immunogenic fragment thereof.
(canceled)
Dependencies are inferred from the claim text.