Use of microbial communities for human and animal health
AssigneesUniversiteit Gent, Microbial Resource Management Health NV (MRM Health)
InventorsSam POSSEMIERS, Massimo MARZORATI, Tom VAN DE WIELE, Ilse SCHEIRLINCK, Pieter VAN DEN ABELLE, Selin BOLCA, Davide GOTTARDI
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Abstract
The disclosure relates to a mixture of bacteria belonging to at least six or seven different and specific bacterial species preferably for use in preventing or treating gastro-intestinal disorders. Preferably, the mixture of bacteria is grown together in a fermenter prior to administering the mixture to a subject in order to prevent or treat the disorder.
Claims30
A method for reduction of symptoms associated with a gastro-intestinal condition, comprising:
- administering a composition to a subject having a gastro-intestinal condition, wherein the composition comprises:
- bacterial members, wherein the bacterial members comprise:
- at least one short chain fatty acid (SCFA) producing bacterial member;
- and
- at least one SCFA metabolizing bacterial member, wherein when the composition is cultured under acidic and low oxygen conditions the at least one short chain fatty acid (SCFA) producing bacterial member is present in an amount sufficient for providing a SCFA sufficient for supporting growth of the at least one SCFA metabolizing bacterial member.
A method for reduction of inflammation, comprising:
- administering to a subject having inflammation a composition, wherein the composition comprises:
- bacterial members, wherein the bacterial members comprise:
- at least one short chain fatty acid (SCFA) producing bacterial member;
- and
- at least one SCFA metabolizing bacterial member, wherein when the composition is cultured under acidic and low oxygen conditions the at least one short chain fatty acid (SCFA) producing bacterial member is present in an amount sufficient for providing a SCFA sufficient for supporting growth of the at least one SCFA metabolizing bacterial member.
A method for reduction of inflammatory intestinal bacteria, comprising:
- administering to a subject a composition, wherein the composition comprises:
- bacterial members, wherein the bacterial members comprise:
- at least one short chain fatty acid (SCFA) producing bacterial member;
- and
- at least one SCFA metabolizing bacterial member, wherein when the composition is cultured under acidic and low oxygen conditions the at least one short chain fatty acid (SCFA) producing bacterial member is present in an amount sufficient for providing a SCFA sufficient for supporting growth of the at least one SCFA metabolizing bacterial member, and wherein the composition provides for a reduction in inflammatory intestinal bacteria when measured by bacterial analysis of fecal matter of the subject prior to and after the administering.
Dependencies are inferred from the claim text.