Back to results
US 2022/0023260 A1Published application
Ready to Use Ketorolac Formulations
AssigneeRtu Pharmaceuticals, LLC
InventorsJoseph V. Pergolizzi, Alexander Mironov, Chad James Pickens, Douglas Giles Johnson
Life of this patent
Estimating the term…
Abstract
Disclosed in certain embodiments is a pharmaceutical composition for parenteral administration comprising: an aqueous solution comprising ketorolac or a pharmaceutically acceptable salt thereof in an amount from about 0.1 mg/mL to about 10 mg/mL; and a pharmaceutically acceptable excipient; wherein the formulation is substantially free of alcohol.
Claims21
A pharmaceutical composition for parenteral administration comprising:
- an aqueous solution comprising ketorolac or a pharmaceutically acceptable salt thereof in an amount form about 0.1 mg/mL to about 10 mg/mL;
- and
- a pharmaceutically acceptable excipient
- wherein the formulation is substantially free of alcohol.
- a pharmaceutically acceptable excipient selected from the group consisting of anhydrous or hydrous forms of sodium chloride, dextrose, sucrose, xylitol, fructose, glycerol, sorbitol, mannitol, potassium chloride, mannose, calcium chloride, magnesium chloride;
- wherein the composition is substantially free of alcohol, has a pH from about 4.5 to about 8.5 and maintains at least 90% of the amount of ketorolac or a pharmaceutically acceptable salt thereof after storage for 6 months at 25° C.;
- and
- wherein the composition is contained in a pharmaceutically acceptable container selected from the group consisting of intravenous bags and intravenous bottles.
5 more elements
21-110. (canceled)
Dependencies are inferred from the claim text.