Hydration gel particle for chemoembolization comprising biodegradable polymer
AssigneeNextbiomedical Co., Ltd.
InventorsYi Xian LI, Choong Ryeol CHOI
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Abstract
The present invention relates to microparticles that can be used as drug-loaded hydrogel particles for embolization and a method for manufacturing same. The microparticles of the present invention have a very excellent anticancer agent adsorption ability, a short anticancer agent adsorption time, and a controllable decomposition time when administered in vivo. Therefore, when the microparticles of the present invention are used in chemoembolization, not only the anticancer effect is excellent, but also side effects can be minimized.
Claims21
Microparticles comprising:
- (a) gelatin, collagen, or a mixture thereof;
- and (b) a biodegradable anionic polymer.
-7. (canceled)
The microparticles of claim 7, wherein the drug is an anticancer drug.
A method for manufacturing microparticles, the method comprising:
- (a) dissolving gelatin, collagen, or a mixture thereof in an aqueous solvent;
- (b) dissolving a biodegradable anionic polymer in an aqueous solvent;
- and
- (c) mixing the solution of gelatin, collagen, or the mixture thereof and the biodegradable anionic polymer solution.
Dependencies are inferred from the claim text.