Cosmetic compositions and methods of use
AssigneesStc.Unm, K&K Biotech
InventorsKristina Trujillo, Katie Uilk, David L. Vander Jagt, Lorraine M. Deck
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Abstract
The present invention relates to substituted stilbenes and dienones which exhibit unexpected dual activity, as inhibitors of NFKB and as agonists (activators) of Nrf2. In particular, these compounds show dual activity and it has been discovered that these compounds are particularly useful in the treatment of certain cosmetic applications and in rejuvenating and beautifying skin and other keratinous tissue of a subject in need. Cosmetic compositions and methods of using said compositions in combination with other components are disclosed herein.
Claims26
A cosmetic composition for use in the treatment, repair, rejuvenation and/or beautification of the skin, including enhancing skin elasticity, the composition comprising an effective amount of at least one compound which exhibits dual activity as a NF-κB signaling inhibitor and a Nrf2 signaling agonist in combination with at least one additional cosmetic additive.
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A method of treating a cosmetic condition of the keratinous tissue of a subject comprising administering to the subject a composition comprising an effective amount of at least one compound which exhibits dual activity as a NF-κB signaling inhibitor and a Nrf2 signaling agonist, in combination with at least one cosmetic additive, wherein said cosmetic condition is wrinkled skin, acne scars, non-acne scars that won't heal, stretch marks, rashes, damaged skin, rough skin, warts and other skin imperfections, skin discoloration, rashes from poison ivy and poison oak and other environmental insults.
20-23. (canceled)
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Dependencies are inferred from the claim text.