Electric Field Application for Single Shot Cardiac Ablation by Irreversible Electroporation

An electroporation ablation system for treating target tissue, the electroporation ablation system comprising:

• an ablation catheter including:
• a handle;
• a shaft having a distal end and defining a longitudinal axis of the ablation catheter;
• and
• an electroporation electrode arrangement at the distal end of the shaft and including a plurality of electrodes arranged so as to define a plurality of electrode pairs each configured to generate an electric field when an electrical pulse sequence is delivered thereto, the plurality of electrode pairs including:
• a first electrode pair arranged so as to generate a first electric field having a first orientation relative to the longitudinal axis when a first electrical pulse sequence is delivered thereto;
• and
• a second electrode pair arranged so as to generate a second electric field having a second orientation relative to the longitudinal axis when a second electrical pulse sequence is delivered thereto;
• and
• an electroporation generator operatively coupled to the electroporation electrode arrangement and configured to selectively generate and deliver the first electrical pulse sequence to first electrode pair, and the second electrical pulse sequence to the second electrode pair.