Drug delivery via mechanical vibration balloon

A drug-delivery device for vessels comprising:

• a catheter body having at least one lumen extending longitudinally therethrough;
• an elongate ultrasound transmission member extending longitudinally through the lumen, the elongate ultrasound transmission member having a distal portion and a proximal end configured to be coupled to an ultrasound transducer;
• an inflatable balloon having an exterior surface, the inflatable balloon coupled to the distal portion of the elongate ultrasound transmission member;
• a plurality of support wires connected to the elongate ultrasound transmission member at two locations;
• and
• a coating of at least one drug on the exterior surface of the inflatable balloon.

A drug-delivery device for vessels comprising:

• an elongate ultrasound transmission member extending longitudinally through a lumen of a catheter body, the elongate ultrasound transmission member having a distal portion and a proximal end configured to be coupled to an ultrasound transducer;
• an inflatable balloon having an exterior surface, the inflatable balloon coupled to the distal portion of the elongate ultrasound transmission member;
• a plurality of support wires connected to the elongate ultrasound transmission member at a proximal joint and a distal joint;
• and
• a coating of at least one drug on the exterior surface of the inflatable balloon.

A drug-delivery device for vessels comprising:

• an elongate ultrasound transmission member extending longitudinally through a lumen of a catheter body, the elongate ultrasound transmission member having a distal portion and a proximal end configured to be coupled to an ultrasound transducer, the elongate ultrasound transmission member having a continuous taper in a direction extending distally from the proximal end of the elongate ultrasound transmission member;
• an inflatable balloon having an exterior surface, the inflatable balloon coupled to the distal portion of the elongate ultrasound transmission member, the inflatable balloon having a distal tip, the distal tip having a guidewire lumen;
• a plurality of support wires connected to the elongate ultrasound transmission member at a proximal joint and a distal joint;
• and
• a coating of at least one drug on the exterior surface of the inflatable balloon.