Seizure detection via electrooculography (eog)
AssigneeEysz, Inc.
InventorsRachel Kuperman, Bikramjit Sarkar, Parth Amin
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Abstract
This invention incorporates analysis of electrooculographic (EOG) data into a methods and apparatus for reporting, alarming and intervening events and conditions. More particularly, EOG signals are analyzed separately from EEG signals, with the EOG signals used as a distinct source of information. The approach can identify patterns associated or predictive of seizures, syncope, drowsiness and loss of consciousness during night or day through the analysis of eye-movements recorded using just the EOG.
Claims11
A method comprising:
- detecting one or more electrooculographic (EOG) signals for each of a left eye and/or right eye of a subject;
- converting the one or more EOG signals to EOG time series data;
- storing the EOG time series data;
- and
- analyzing the stored EOG time series data to provide an output indicative and/or predictive of seizures, syncope, drowsiness, loss of consciousness, or other neurological events or conditions of the subject.
A method for controlling seizures of a human subject using electrooculographic (EOG) signals comprising:
- collecting electroencephalographic (EEG) signals from the human subject;
- separating EOG signals indicative of ocular muscle activation for each of a left eye and right eye from the EEG signals;
- converting the EOG signals into EOG time series data;
- storing the EOG time series data;
- temporally segmenting the EOG time series data to provide temporally segmented EOG data;
- pre-processing the temporally segmented EOG data with one or more signal processing steps to provide preprocessed EOG data;
- obtaining a training data set including labels for EOG data known to be indicative of seizures;
- training a neural network using the training data set and the temporally segmented EOG data;
- matching the preprocessed EOG data against the neural network;
- and
- further controlling a seizure in the human subject by one or more of
- producing an alarm;
- further communicating with a neurostimulation or other closed-loop device—such as a Vagus Nerve Stimulator (VNS) or Responsive Neurostimulation System (RNS).
Dependencies are inferred from the claim text.