Non-invasive Glucose Sensor
AssigneeEcole Polytechnique Federale De Lausanne (Epfl)
InventorAssim Boukhayma
Life of this patent
Estimating the term…
Abstract
An optical device for the in noninvasive determination of the concentration of glucose or another analyte in blood using a combination of Raman spectrometry and PPG. The device includes an optical detector, preferably a CMOS imager including pinned photodiodes (PPD) to collect a time-variable signal and a logic circuit arranged to determine a glucose concentration based on variations in the optical signal happening in a frequency range compatible with the cardiac rhythm.
Claims18
An optical device for the in-vivo determination of a concentration of an analyte in blood, comprising:
- an optical interface for optical coupling to a sensed region of the body;
- a light source arranged for transmitting UV, visible or infrared light to the sensed region
- an optical collection system receiving a scattered light from the sense region;
- an optical detector, generating a time-variable signal influenced by the concentration of the analyte;
- a logic circuit, arranged to determine the concentration of the analyte in blood in the sense region based on the time-variable signals.
Method of noninvasive determination of the concentration of an analyte in a part of the body, comprising:
- illuminating a sensed region of the body with an essentially monochromatic visible or infrared light;
- receiving light scattered from the sensed region;
- determining the intensity of a component of the scattered light imputable to Raman scattering of the analyte;
- determining from the scattered light a time-variable PPG signal indicative of the amount of blood present in the sense region;
- and
- determining the concentration based on the intensity of said component and on the PPG signal.
Dependencies are inferred from the claim text.