Detection method and detection device
AssigneePanasonic Intellectual Property Management Co., Ltd.
InventorSATOSHI ARIMOTO
Life of this patent
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Abstract
A target substance detection method includes forming a complex by causing a target substance and a dielectric particle to bind to each other, the dielectric particle being modified with a substance (for example, an antibody) having a property of specifically binding to the target substance; subjecting a bound particle and an unbound particle to dielectrophoresis in a liquid, the bound particle being the dielectric particle constituting the complex, the unbound particle being a dielectric particle not constituting the complex; and detecting the target substance in the complex, based on a difference in motion between the bound particle and the unbound particle caused by the dielectrophoresis.
Claims5
A detection method comprising:
- forming a complex by causing a target substance and a dielectric particle to bind to each other, the dielectric particle being modified with a substance having a property of specifically binding to the target substance;
- subjecting a bound particle and an unbound particle to dielectrophoresis in a liquid, the bound particle being the dielectric particle constituting the complex, the unbound particle being a dielectric particle not constituting the complex;
- and
- detecting the target substance included in the complex, based on a difference in motion between the bound particle and the unbound particle caused by the dielectrophoresis, wherein
- a rotating electric field is produced in the liquid to subject the bound particle and the unbound particle to the dielectrophoresis,
- the bound particle moves to draw a circular path by the dielectrophoresis, and
- the unbound particle rotates around an axis passing through a center position of the unbound particle by the dielectrophoresis.
A detection device comprising:
- a dielectrophoresis device that subjects a bound particle and an unbound particle to dielectrophoresis in a liquid, the bound particle being a dielectric particle constituting a complex, the unbound particle being a dielectric particle not constituting the complex, the complex being a complex of a target substance that has bound to a dielectric particle modified with a substance having a property of specifically binding to the target substance;
- and
- a detector that detects the target substance included in the complex, based on a difference in motion between the bound particle and the unbound particle caused by the dielectrophoresis, wherein
- the dielectrophoresis device produces a rotating electric field in the liquid to subject the bound particle and the unbound particle to the dielectrophoresis,
- the bound particle moves to draw a circular path by the dielectrophoresis, and
- the unbound particle rotates around an axis passing through a center position of the unbound particle by the dielectrophoresis.
Dependencies are inferred from the claim text.