Back to results
US 2022/0017567 A1Published application
Methods of generating nanoarrays and microarrays
AssigneeNautilus Biotechnology, Inc.
InventorsDmitriy GREMYACHINSKIY, Rachel GALIMIDI, Parag MALLICK, Sujal M. PATEL
Life of this patent
Estimating the term…
Abstract
The methods described herein provide a means of producing an array of spatially separated proteins. The method relies on covalently attaching each protein of the plurality of proteins to a structured nucleic acid particle (SNAP), and attaching the SNAPs to a solid support.
Claims17
A method of producing an array of different proteins, comprising:
- (a) attaching a plurality of structured nucleic acid particles to a plurality of different proteins, such that each of the plurality of structured nucleic acid particles is attached to only one protein of the plurality of different proteins;
- and
- (b) attaching the plurality of structured nucleic acid particles to an array of attachment sites on a solid support, such that each of the array of attachment sites is attached, via a structured nucleic acid particle, to only one protein of the plurality of different proteins, thereby producing the array of different proteins.
The method of claim 12, wherein the structured nucleic acid particle has a diameter of at least 75 nanometers.
Dependencies are inferred from the claim text.